In vitro and in silico tools for studying heterotypic gap junction channel properties

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Title In vitro and in silico tools for studying heterotypic gap junction channel properties
Publication Type dissertation
School or College College of Engineering
Department Biomedical Engineering
Author Mondal, Abhijit
Date 2017-05
Description We have developed and tested new in vitro and in silico tools for studying gap junctions at the tissue and single channel level, respectively. We believe this work contributes toward expanding the field of gap junction within the available experimental and computational limits. The PerFlexMEA has the potential to be a potent tool for electrophysiological studies in fibrotic and arrhythmic cardiac tissues. Our in silico studies have revealed a new physiological mechanism that needs to be further investigated in vitro.
Type Text
Subject Bioengineering--Research--United States; Gap junctions (Cell biology)
Dissertation Institution University of Utah
Dissertation Name Doctor of Philosophy
Language eng
Rights Management Copyright © Abhijit Mondal 2017
Rights License http://rightsstatements.org/vocab/InC/1.0/
Format application/pdf
Format Medium application/pdf
Conversion Specifications Original scanned with Kirtas 2400 and saved as 400 ppi uncompressed TIFF. PDF generated by Tesseract for online display.
ARK ark:/87278/s6h746xp
Setname ir_etd
ID 1253305
Reference URL https://collections.lib.utah.edu/ark:/87278/s6h746xp
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