Binocular Acuity Summation (BAS) in Multiple Sclerosis (MS)

The afferent visual pathway (AVP) is commonly involved in MS and neuromyelitis optica (NMO). Patients with/without history of acute optic neuritis (ON) can have inter-ocular differences (IOD) in visual acuity (VA), especially at low-contrast levels, which interfere with BAS. BAS is defined as the degree to which binocular vision is greater than VA of the better eye. Reductions in binocular visual functioning may impair depth/motion perception with important quality of life ramifications.(1,2,3) We determined the relation of BAS to scores for structural, functional and electrophysiological measures of the AVP in an MS/NMO cohort.