Alpha2 Modulation of Intracellular CA++ Signal in the Inner Plexiform Layer (IPL) of the Rat Retina

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Identifier 20070213_nanos_posters_094.pdf
Title Alpha2 Modulation of Intracellular CA++ Signal in the Inner Plexiform Layer (IPL) of the Rat Retina
Creator Cun-Jian Dong; Yuan-Xing Guo; Larry Wheeler; William A. Hare
Affiliation Allergan, Inc., Irvine, CA
Subject Inner Plexiform Layer; Alpha2-Adrenergic Agonist; Calcium Channel Blocker; Brimonidine; Retinal Ganglion Cell
Description There is compelling evidence from animal models of glaucoma and acute retinal ischemia that ?2 agonists protect retinal ganglion cells (RGCs) from injury. However, the mechanism of action is not well understood. We explored the role of the ?2 adrenergic system in modulation of intracellular Ca++ signaling at the IPL where communication between RGCs and their presynaptic cells takes place.
Date 2007-02-13
Language eng
Format application/pdf
Type Text
Source 2007 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2007: Poster Presentations
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6xm1n0b
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Setname ehsl_novel_nam
ID 181415
Reference URL https://collections.lib.utah.edu/ark:/87278/s6xm1n0b
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