Clonally-Expanded Plasma Cells in Neuromyelitis Optica Cerebrospinal Fluid Produce IgG Against Aquaporin-4

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Identifier 20090224_nanos_sciplatform_08.pdf
Title Clonally-Expanded Plasma Cells in Neuromyelitis Optica Cerebrospinal Fluid Produce IgG Against Aquaporin-4
Creator Jeffrey Bennett; Chiwah Lam; Katherine Bautista; Cecily DuPree; Magdalena Glogowska; David Case; Philippe Saikali; Jack Antel; Sudhakar Reddy; Bernhard Hemmer; Gregory Owens; Donald Gilden
Affiliation (JB) (CL) (KB) (CD) (MG) (DC) (GO) (DG) University of Colorado Denver, Aurora, CO; (PS) (JA) Montreal Neurological Institute, Montreal, QC, Canada; (SR) (BH) Technische Universitat, Munich, Germany
Subject neuromyelitis optica; aquaporin-4; plasma cells; optic neuritis
Description Neuromyelitis optica immunoglobulin G (NMO-IgG) binds the aquaporin-4 (AQP-4) water channel of astrocytes that are abundant in the perivessel and subpial areas of the brain. NMO-IgG appears specific for NMO and is now included as a diagnostic criterion for disease.
Date 2009-02-24
Language eng
Format application/pdf
Type Text
Source 2009 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2009: Scientific Platform Presentations (Session II)
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s66d90cv
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Setname ehsl_novel_nam
ID 180546
Reference URL https://collections.lib.utah.edu/ark:/87278/s66d90cv
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