Evaluating the Role of Electroretinography in Patients with Optic Neuritis

Electroretinography (ERG) has potential as a quantitative and objective measure of retinal and optic nerve function for patients with optic neuritis (ON). Multi-focal (mf) ERG response represents cone and bipolar cell activity, whereas the photopic negative response (PhNR) is more specific to ganglion cell activity. This study will investigate the clinical utility of ERG in prognostication of visual outcomes. ERG might be utilized to assess early response to neuroprotective agents following ON onset, when structural methods such as optical coherence tomography (OCT) are confounded by edema.