Identifier |
20230312_nanos_posters_016 |
Title |
Targeted Cancer Therapy Associated Optic Neuropathy at a U.S. Tertiary Cancer Center |
Creator |
May Ameri; David Szynkarski; Atish Amin; Nagham Al-Zubidi |
Affiliation |
(MA) McGovern - Houston, TX; (DS) UTMB; (AA) University of Texas Medical Branch at Galveston; (NAZ) MD Anderson Cancer Center |
Subject |
Optic Neuropathy; Optic Neuritis |
Description |
Targeted Cancer therapy (TCT) has transformed the field of oncology. TCT is a novel treatment modality that harnesses the patient's own immune system to target cancer and block tumor cells from deactivating the immune system. TCT works successfully on tumors that were previously difficult to treat, leading to improved prognosis in advanced metastatic tumors. TCT has been associated with a broad spectrum of side effects called immune-related adverse events (irAEs). Neuro-ophthalmic irAEs occur in 0.46% of patients on TCT and may affect the afferent and efferent visual systems. TCT-associated optic neuropathy has been reported in the literature as either optic neuritis, arteritic or non-arteritic anterior ischemic optic neuropathy. Our study aims to identify the presentation and characteristics of different forms of TCT-related optic neuropathy and clinical outcomes. |
Date |
2023-03-14 |
References |
Yu CW, Yau M, Mezey N, Joarder I, Micieli JA. Neuro-ophthalmic Complications of Immune Checkpoint Inhibitors: A Systematic Review. Eye Brain. 2020 Nov 3;12:139-167. doi: 10.2147/EB.S277760. PMID: 33173368; PMCID: PMC7648547. |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2023 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2023: Poster Session I: Disorders of the Anterior Visual Pathway (Retina, Optic Nerve, and Chiasm) |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s65bz7fk |
Setname |
ehsl_novel_nam |
ID |
2335223 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s65bz7fk |