REFLECT Trial: Efficacy and Safety of Bilateral Gene Therapy for Leber Hereditary Optic Neuropathy
| Identifier | 20220215_nanos_sciplatform3_06 |
| Title | REFLECT Trial: Efficacy and Safety of Bilateral Gene Therapy for Leber Hereditary Optic Neuropathy |
| Creator | Nancy J. Newman; Patrick Yu-Wai-Man; Valerio Carelli; Prem Subramanian; Mark Moster; An-Guor Wang; Sean Donahue; Bart Leroy; Valérie Biousse; Catherine Vignal-Clermont; Alfredo Sadun; Gema Rebolleda Fernández; Elizabeth Fortin; Rudrani Banik; Laure Blouin; Michel Roux; Magali Taiel; José-Alain Sahe |
| Affiliation | (NJN) (VB) Emory University School of Medicine, Atlanta, GA; (PYWM) Moorfields Eye Hospital, London, United Kingdom of Great Britain and Northern Ireland; (VC) IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; (PS) University of Colorado School of Medicine, Aurora, CO; (MM) Wills Eye Hospital, Philadelphia, PA; (AGW) Taipei Veterans General Hospital, Taipei, Taiwan; (SD) Vanderbilt Eye Institute, Nashville, TN; (BL) Ghent University Hospital, Ghent, Belgium; (CVC) Centre Hospitalier National d'Ophtalmologie des Quinze Vingts, Paris, France; (AS) Doheny Eye Institute, Los Angeles, CA; (GRF) Ramon y Cajal Hospital,Madrid, Spain; (EF) Massachusetts Eye and Ear Infirmary, Boston, MA; (RB) Icahn School of Medicine at Mount Sinai, New York, NY; (LB) (MR) (MT) GenSight Biologics, Paris, France; (JAS) University of Pittsburgh School of Medicine, Pittsburgh, PA |
| Subject | Genetic Disease; Optic Neuropathy; Retina |
| Description | Leber Hereditary Optic Neuropathy (LHON) is a blinding orphan disease leading to bilateral vision loss. Lenadogene nolparvovec (rAAV2/2-ND4) is a gene therapy developed for the treatment of LHON caused by a mutation in the ND4 gene. |
| Date | 2022-02 |
| Language | eng |
| Format | application/pdf |
| Format Creation | Microsoft PowerPoint |
| Type | Text |
| Source | 2022 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of | NANOS Annual Meeting 2022: Scientific Platform Session III |
| Collection | Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher | North American Neuro-Ophthalmology Society |
| Holding Institution | Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management | Copyright 2022. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK | ark:/87278/s6dv7xd9 |
| Setname | ehsl_novel_nam |
| ID | 2191987 |
| Reference URL | https://collections.lib.utah.edu/ark:/87278/s6dv7xd9 |