| Identifier |
20220213_nanos_posters_210 |
| Title |
Mydriasis as a Side Effect of Dinutuximab Immunotherapy in Pediatric Neuroblastoma: A Case Series |
| Creator |
Adam M. Kruszewski; Julia Reid; Ayesha Malik; John Maris; Grant Liu |
| Affiliation |
(AK) University of Pennsylvania, Departments of Neurology and Ophthalmology, Philadelphia, Pennsylvania; (JR) (AM) (GL) Children's Hospital of Philadelphia, Division of Ophthalmology, Philadelphia, Pennsylvania; (JM) Children's Hospital of Philadelphia, Division of Oncology, Philadelphia, Pennsylvania |
| Subject |
Pediatric Neuro-ophthalmology; Pupil; Chemotherapy and Radiation Injury; Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid) |
| Description |
Dinutuximab is a monoclonal antibody against disialoganglioside GD2, a glycosphingolipid strongly expressed on neuroblastoma cells and minimally expressed on normal peripheral nerve cells. While dinutuximab improves survival in high-risk pediatric neuroblastoma, it has also been reported to cause side effects of peripheral neuropathy that typically involve the limbs. We report three cases of children with neuroblastoma who developed mydriasis following treatment with dinutuximab. |
| Date |
2022-02 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2022 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2022: Poster Session I: Pediatric Neuro-Ophthalmology |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2022. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6ekvnz3 |
| Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
| Setname |
ehsl_novel_nam |
| ID |
2063404 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6ekvnz3 |
