Identifier |
20190319_nanos_sciplatform3_03_slides |
Title |
Amnion-derived Multipotent Progenitor Cells Attenuate Optic Nerve and Spinal Cord Demyelinating Disease |
Creator |
Kenneth Shindler; Reas Khan; Kimberly Dine; Ahmara Ross; Keirnan Willett; Rick Banas; Larry Brown |
Affiliation |
(KS) (RK) (KD) (AR) (KW) University of Pennsylvania, Philadelphia; (RB) (LB) Noveome Biotherapeutics, Inc., Pittsburgh |
Subject |
Neuro-Ophth & Systyemic Disease (eg. MS, MG, Thyroid); Optic Neuropathy; Demeylinating Disease |
Description |
ST266 is the biological secretome of Amnion-derived Multipotent Progenitor (AMP) cells. ST266 proteins accumulate in eyes and optic nerves following intranasal delivery, resulting in selective suppression of optic neuritis in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis, without suppressing spinal cord lesions. We tested the hypothesis that systemic AMP cell administration could suppress both optic neuritis and myelitis in EAE. |
Date |
2019-03 |
Language |
eng |
Format |
application/pdf |
Format Creation |
Microsoft PowerPoint |
Type |
Text |
Source |
2019 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2019: Scientific Platform III |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6n05tc5 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
1455035 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6n05tc5 |