Identifier |
20190319_nanos_posters_201 |
Title |
Elamipretide (MTP-131) Topical Ophthalmic Solution for the Treatment of Leber's Hereditary Optic Neuropathy |
Creator |
Rustum Karanjia; Alfredo Sadun |
Affiliation |
(RK) (AS) Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, Pasadena, CA |
Subject |
Optic Neuropathy; Genetic Disease |
Description |
Leber's Hereditary Optic Neuropathy is a mitochondrial disease characterized by sudden and profound vision loss in both eyes. Elamipretide is has been demonstrated to colocalize with cardiolipin in the inner membrane of mitochondria, where it is thought to improve mitochondrial bioenergetics. The purpose of this study was to look at the safety, tolerability and potential efficacy of the topical Elamipretide in patients affected with LHON. |
Date |
2019-03 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2019 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NAM 2019: Poster Session II: Scientific Advancements in Neuro-Ophthalmology |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6fb9mnc |
Setname |
ehsl_novel_nam |
ID |
1432859 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6fb9mnc |