Optic neuritis occurs during multiple sclerosis (MS) and induces retinal ganglion cell (RGC) loss. Thus, neuroprotective therapies are needed. We previously showed that intranasally delivered ST266, the biological secretome of Amnion-derived Multipotent Progenitor cells, attenuated loss of vision and RGCs in experimental optic neuritis, but mechanisms of its actions are not known. Potential mechanisms were examined in the experimental autoimmune encephalomyelitis (EAE) model of MS.
Date
2017
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
2017 North American Neuro-Ophthalmology Society Annual Meeting