Acute cerebral venous sinus thrombosis (CVT) presenting with papilledema and complete vision loss

The evaluation of optic disc edema can be a diagnostic challenge. It is important to perform thorough work-up to rule-out vascular, infectious, inflammatory, toxic, metabolic, and compressive causes. Papilledema is present in only approximately 28% of patients with CVT. Papilledema commonly causes transient visual impairment, but if left untreated, can lead to permanent loss due to optic atrophy. Severe vision loss in the setting of acute CVT is rare and reported in only 2%-4% of cases.