Bilateral Tonic Pupils Due to Antidisialoganglioside Antibody Immunotherapy for Neuroblastoma

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Title Bilateral Tonic Pupils Due to Antidisialoganglioside Antibody Immunotherapy for Neuroblastoma
Creator C. Swiston; A. Jebaraj; S. Vegunta; J. Warner
Affiliation John A. Moran Eye Center, Salt Lake City, Utah
Abstract Atonic pupil results from postganglionic parasympathetic pupillomotor denervation, leading classically to mydriasis, poor reaction to light with or without preservation of constriction to accommodation (light-near dissociation), and cholinergic hypersensitivity.
Subject Atonic Pupil; Mydriasis
OCR Text Show
Date 2023-06
Date Digital 2023-06
References 1. Sarao MS, Elnahry AG, Sharma S. Adie Syndrome. Treasure Island, FL: StatPearls Publishing, 2021. 2. Bartholomew J, Washington T, Bergeron S, Nielson D, Saggio J, Quirk L. Dinutuximab: a novel immunotherapy in the treatment of pediatric patients with high-risk neuroblastoma. J Pediatr Oncol Nurs. 2017;34:5-12. 3. Tse BC, Navid F, Billups CA, O'Donnell T, Hoehn ME. Ocular abnormalities in patients treated with a novel anti-GD2 monoclonal antibody, hu14.18K322A. J AAPOS. 2015;19:112- 115. 4. Kremens B, Hero B, Esser J, Weinel P, Filger-Brillinger J, Fleischhack G, Graf N, Grüttner HP, Niemeyer C, Schulz A, Wickmann L, Berthold F. Ocular symptoms in children treated with human-mouse chimeric anti-GD2 mAb ch14.18 for neuroblastoma. Cancer Immunol Immunother. 2002;51:107-110. 5. Svennerholm L, Boström K, Fredman P, Jungbjer B, Lekman A, Månsson JE, Rynmark BM. Gangliosides and allied glycosphingolipids in human peripheral nerve and spinal cord. Biochim Biophys Acta. 1994;1214:115-123.
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, June 2023, Volume 43, Issue 2
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s67gaq23
Setname ehsl_novel_jno
ID 2498906
Reference URL https://collections.lib.utah.edu/ark:/87278/s67gaq23
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