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Evaluation of the retinal nerve fiber layer: descriptive or predictive?

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Title Journal of Neuro-Ophthalmology, September 2009 Volume 29, Issue 3
Date 2009-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6hb2b9j
Setname ehsl_novel_jno
ID 226265
Reference URL https://collections.lib.utah.edu/ark:/87278/s6hb2b9j

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Title Evaluation of the retinal nerve fiber layer: descriptive or predictive?
Creator Peter J. Savino
Affiliation Shiley Eye Center, University of California-San Diego, 9415 Camp Point Drive, La Jolla, CA 92093-0946, USA.
Abstract For nearly a century, ophthalmologists have recognized that thinning of the retinal nerve fiber layer (rNFL) could be observed ophthalmoscopically in diseases of the optic nerve. Using high-resolution red-free fundus photography, Hoyt found slit-like rNFL defects that corresponded to visual field defects in glaucoma. Frisn extended these observations to multiple sclerosis, predicting the later discovery that axonal loss occurs in the retina without clinical bouts of optic neuritis. In measurement of the rNFL, red-free fundus photography has been superseded by more widely available, robust, and quantitative retinal imaging techniques, including Heidelberg retinal tomography, scanning laser polarimetry, and optical coherence tomography (OCT). Having emerged as the technique of choice in measuring the rNFL, OCT has shown that the degree of preoperative rNFL thinning reliably predicts whether vision will recover after surgery for pituitary adenoma. Such quantitative studies of the rNFL have the potential, therefore, of providing descriptive and predictive information that will be valuable in clinical care.
Subject Diagnostic Techniques, Ophthalmological; Female; History, 20th Century; Humans; Middle Older people; Optic Nerve Diseases; Predictive Value of Tests; Prognosis; Retina; Retinal Ganglion Cells; Tomography, Optical Coherence; Wallerian Degeneration
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 226259
Reference URL https://collections.lib.utah.edu/ark:/87278/s6hb2b9j/226259
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