Retinal Ganglion Cell Loss Precedes Retinal Nerve Fiber Thinning in Nonarteritic Anterior Ischemic Optic Neuropathy

Update Item Information
Title Retinal Ganglion Cell Loss Precedes Retinal Nerve Fiber Thinning in Nonarteritic Anterior Ischemic Optic Neuropathy
Creator Mohammadreza Akbari, MD; Parisa Abdi, MD; Masoud Aghsaei Fard, MD, FICO; Marjan Afzali, MD; Ahmad Ameri, MD; Alireza Yazdani-Abyaneh, MD; Massod Mohammadi, MD; Sasan Moghimi, MD
Affiliation Eye Research Center, Department of Neuro-Ophthalmology, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
Abstract Analysis of retinal nerve fiber layer thickness and macular ganglion cell layer loss provides a noninvasive method to assess optic chiasmal compression. These techniques may provide valuable data for patient evaluation and management when combined with findings on clinical examination and neuroimaging results.; ; Data from 20 eyes of 10 patients with pituitary tumor treated at Inha University Hospital from 2011 to 2013 were collected. This included results of ophthalmologic examination, fundus photography, spectral domain optical coherence tomography (SD-OCT), automated visual field testing, and brain magnetic resonance imaging (MRI). Abnormal color patterns on thickness and deviation maps obtained by macular ganglion cell analysis (GCA) were evaluated and compared with visual field defects.; ; Patients with pituitary tumor showed preferential ganglion cell loss in the nasal hemiretina and characteristic vertical midline-respecting perimacular ganglion cell-inner plexiform layer defects, which anatomically matched the visual field defects.; ; Macular GCA using SD-OCT can be used to complement visual field assessment and brain MRI findings during evaluation of patients with pituitary tumor.
Subject Female; Humans; Macula Lutea; Magnetic Resonance Imaging; Male; Middle Older people; Nerve Fibers; Optic Disk; Pituitary Neoplasms; Retinal Diseases; Retinal Ganglion Cells; Tomography, Optical Coherence; Visual Acuity; Visual Fields
OCR Text Show
Date 2016-06
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, June 2016, Volume 36, Issue 2
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s69d0rxn
Setname ehsl_novel_jno
ID 1276489
Reference URL https://collections.lib.utah.edu/ark:/87278/s69d0rxn
Back to Search Results