| Identifier |
walsh_2016_s2_c4-2 |
| Title |
A Night at the Met - Path PPT |
| Creator |
Clotilde Hainline; Janet C. Rucker; David Zagzag; Yvonne W. Liu; Floyd A. Warren; Laura J. Balcer; Steven L. Galetta |
| Affiliation |
(CH) (JCR) (FAW) (LJB) (SLG) NYU Langone Medical Center, Department of Neurology New York, NY; (JCR) (FAW) (LJB) (SLG) NYU Langone Medical Center, Department of Ophthalmology New York, NY; (DZ) NYU Langone Medical Center, Microvascular and Molecular Neuro-Oncology Laboratory New York, NY; (DZ) NYU Langone Medical Center, Division of Neuropathology New York, NY; (DZ) NYU Langone Medical Center, Department of Neurosurgery New York, NY; (YWL) NYU Langone Medical Center, Department of Radiology New York, NY; (LJB) NYU Langone Medical Center, Department of Population Health New York, NY |
| Subject |
Vision Loss; Visual Field; Prosopagnosia; Cerebral Amyloid Angiopathy; Amyloid-Beta Related Angiitis; Intracerebral Hemorrhage Intracerebral Hemorrhage |
| History |
A 73-year old woman with no headache history presented to the emergency department with several days of right-sided, retro-ocular, and vertex headaches and inability to see the left side of the TV screen-- all beginning 1 week after cataract surgery. Evaluation by her ophthalmologist was unrevealing. Eight years earlier, she had been diagnosed with stage 1a lung adenocarcinoma and had undergone wedge resection. One year later, she developed hematuria and left arm edema. A bladder scan showed increased uptake, and she was diagnosed with metastatic stage 3 bladder cancer. She was considered in remission from both malignancies. On our examination, she was normotensive. Visual acuities were 20/20 OD and 20/25 OS. Color vision was normal. Pupils were symmetric and brisk without APD. She had a left homonymous hemianopia to confrontation. The remainder of the examination was normal. Brain CT showed a 2 cm right occipitotemporal hemorrhage with surrounding edema. Brain MRI was consistent with an acute hematoma, showing subtle patchy rim enhancement and a suggestion of smooth thin dural or leptomeningeal enhancement over the right hemisphere. Gradient echo MRI showed no microhemorrhages. CT angiogram (to look for an underlying AVM), and CT of the chest/abdomen/pelvis (to look for primary malignancy) were negative. Three weeks later, she developed prosopagnosia. Brain MRI showed several new lesions adjacent to the original hemorrhage. There were new hemorrhages in the original lesion and more prominent peripheral enhancement. Echocardiogram to exclude marantic endocarditis was unremarkable. Digital cerebral angiography was normal. A procedure was performed. |
| Disease/Diagnosis |
Amyloid beta-related angiitis. |
| Date |
2016-02 |
| References |
Jacobs DA, Liu GT, Nelson PT, Galetta SL. Primary Central Nervous System Angiitis, Amyloid Angiopathy, and Alzheimer's Pathology Presenting with Balint's Syndrome. Survey of Ophthalmology 49, 454-459, 2004. Moussaddy A, Levy A, Strbian D, et al. Inflammatory Cerebral Amyloid Angiopathy, Amyloid-β-Related Angiitis, and Primary Angiitis of the Central Nervous System: Similarities and Differences. Stroke 46, 210-213, 2015. Nouth A, Borys E, Gierut A, et al. Amyloid-beta related angiitis of the central nervous system: case report and topic review. Frontiers in Neurology 5, 13, 2014. Scolding NJ, Joseph F, Kirby PA, et al. Aβ-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy. Brain 128, 500-515, 2005. |
| Language |
eng |
| Format |
application/pdf |
| Format Creation |
Microsoft PowerPoint |
| Type |
Text |
| Source |
48th Annual Frank Walsh Society Meeting |
| Relation is Part of |
NANOS Annual Meeting Frank B. Walsh Sessions; 2016 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2016. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6hx499r |
| Setname |
ehsl_novel_fbw |
| ID |
179356 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6hx499r |
