Renal Red Herring

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Identifier walsh_2014_s1_c3-2
Title Renal Red Herring
Creator John J. Chen; John J. Brinkley; Namrata Singh; Amanda C. Maltry; Bruno A. Policeni; Richard C. Allen; Reid A. Longmuir; Matthew J. Thurtell
Affiliation (JJC) (JJB) (ACM) (RCA) (RAL) (MJT) University of Iowa Department of Ophthalmology and Visual Sciences Iowa City, IA; (NS) University of Iowa Department of Internal Medicine Iowa City, IA; (BAP) University of Iowa Department of Radiology Iowa City, IA; (RCA) University of Iowa Department of Otolaryngology Iowa City, IA
Subject Wegener's Granulomatosis; Renal Cell Carcinoma; Diplopia; Optic Neuropathy; Metastasis
History A 71 year-old Caucasian male with a history of Wegener's granulomatosis presented with vision loss OU and horizontal binocular diplopia. His past medical history was significant for Wegener's granulomatosis, which was diagnosed in 2000 on the basis of a renal biopsy. He was previously treated with various combinations of cyclophosphamide, azathioprine, and prednisone. His recent treatment regimen had included oral prednisone (7.5mg daily) and azathioprine (150mg daily). However, against medical advice, he had stopped taking his immunosuppressants for six months prior to his presentation in June 2013. His past history was also remarkable for Graves' disease, atrial fibrillation, hypertension, diabetes, and subdural hematoma in 2008 requiring surgical evacuation.At presentation, he reported a several week history of binocular horizontal diplopia on leftward gaze and concurrent progressive vision loss OS>OD. He also reported mild eye pain OS and occasional epistaxis. On examination, best-corrected visual acuity was 20/50 OD and 20/200 OS. Pupil examination demonstrated a 1.5 log unit RAPD OS without anisocoria. Intraocular pressures were normal. There was 3 mm of relative proptosis OS with a moderate abduction deficit OS. Anterior segment examination revealed cataract OU. Dilated funduscopic examination showed trace temporal optic disc pallor OS. Goldmann visual fields revealed central depression OD and a dense cecocentral scotoma OS. The RNFL thickness was within normal limits OU on optical coherence tomography. B-scan ultrasonography of the orbits revealed a highly-reflective mass superotemporally in the posterior orbit OS. MRI showed a well-circumscribed extraconal lateral orbital mass. CT demonstrated a soft tissue mass in the left orbital apex extending into the superior orbital fissure with associated erosion of the greater wing of the sphenoid, but without associated calcification.A diagnostic procedure was performed.
Disease/Diagnosis Renal cell carcinoma metastasis to the orbit.
Presenting Symptom A 71 year-old Caucasian male with a history of Wegener's granulomatosis presented with vision loss OU and horizontal binocular diplopia.
Neuroimaging Magnetic Resonance Imaging
Treatment Radiation Therapy
Date 2014-03
References None
Language eng
Format video/mp4
Type Image/MovingImage
Source 46th Annual Frank Walsh Society Meeting
Relation is Part of NANOS Annual Meeting Frank B. Walsh Sessions; 2014
Collection Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2014. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s66b015g
Setname ehsl_novel_fbw
ID 179227
Reference URL https://collections.lib.utah.edu/ark:/87278/s66b015g
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