A Mercurial Course

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Identifier walsh_2007_s1_c5
Title A Mercurial Course
Creator Melissa W. Ko, MD; Sashank Prasad, MD; Edward Lee, MD; Nicholas Gonatas, MD; Matthew Stern, MD; Steven Galetta, MD
Affiliation Philadelphia, PA
Subject Diplopia; Gait Ataxia; Creutzfeldt-Jakob Syndrome; Supranuclear Palsy, Progressive
History A 61-year old male with a 9-month history of progressive diplopia, dysarthria, ataxic gait, worsening memory impairment, anxiety depression, sleep disturbances and a 30-pound loss of weight.
Pathology Prion protein disease demonstrated by granular deposition and varying degrees of spongiosis in the caudate and putamen.
Disease/Diagnosis Creutzfeldt Jakob Disease
Clinical Slow vertical saccades; Rebound nystagmus; Impaired vertical and horizontal pursuits
Presenting Symptom Diplopia; Dysarthria; Ataxic gait
Neuroimaging CT; MRI
Date 2007-02
References 1. Grant MP, Cohen M, Petersen RB, et al. Abnormal eye movements in Creutzfeldt-Jakob disease. Annals Neurol 1993; 34(2):192-197. 2. Bertoni JM, Brown P, Goldfarb LG, Rubenstein R, Gajdusek DC. Familial Creutzfeldt-Jakob disease (codon 200 mutation) with supranuclear palsy. JAMA 1992; 268(17):2413-2415. 3. Liu GT, Volpe NJ, Galetta SL. Eye movement disorders: conjugate gaze abnormalities. In Liu GT, Volpe NJ, Galetta SL (eds): Neuro-ophthalmalogy: diagnosis and management. Philadelphia: W.B. Saunders Co., 2001. 4. Shimamura M, Uyama E, Hirano T, Murakami T, Mita S, Kitamoto T, Uchino M. A unique case of sporadic Creutzfeldt-Jacob disease presenting as Progressive Supranuclear Palsy. Internal Med 2003; 42(2): 195-198. 5. Josephs KA, Tsuboi Y, Dickson DW. Creutzfeldt-Jakob disease presenting as progressive supranuclear palsy. European J of Neurol 2004; 11:343-346.
Language eng
Format application/pdf
Type Text
Source 39th Annual Frank Walsh Society Meeting
Relation is Part of NANOS Annual Meeting Frank B. Walsh Sessions; 2007
Collection Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s69g5qkb
Setname ehsl_novel_fbw
ID 178304
Reference URL https://collections.lib.utah.edu/ark:/87278/s69g5qkb
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