A 78 year-old man presented with a one-month history of progressive painless binocular vision loss. He had sustained head trauma without loss of consciousness three days prior to the onset of vision loss. On the morning of his presentation to us, he had awoken with complete binocular vision loss and had been started on oral prednisone (70 mg daily) by his local eye care provider. He denied symptoms of giant cell arteritis. His past medical history was remarkable for hypertension, diabetes, and a distant history of prostate cancer that was thought to be in remission. Neurologic review of systems was unremarkable. Examination revealed no light perception OU. The pupils were dilated and minimally reactive to light. There was no RAPD. Intraocular pressures were within normal limits OU. Extraocular movements were full OU. Anterior segment examination revealed pseudophakia OU. Dilated funduscopic examination revealed diffuse optic atrophy OU. Neurologic examination was unremarkable.
Disease/Diagnosis
Multicentric glioblastoma multiforme involving the optic chiasm
Date
2015-02
References
1. Pallini R et al. Glioblastoma of the optic chiasm. J Neurosurg 1996; 84: 898-899. 2. Synowitz M et al. Multicentric glioma with involvement of the optic chiasm. Clin Neurol Neurosurg 2002; 105: 66-68. 3. Dinh TT et al. Glioblastoma of the optic chiasm. J Clin Neurosci 2007; 14: 502-505. 4. Abou-Zeid A et al. Blindness from multiple cerebral gliomas mimicking metastatic brain disease. Br J Neurosurg 2008; 22: 772-773. 5. Goh JJ et al. Vanishing glioblastoma after corticosteroid therapy. J Clin Neurosci 2009; 16: 1226-1228. 6. Matloob S et al. Multifocal malignant optic glioma of adulthood presenting as acute anterior optic neuropathy. J Clin Neurosci 2011; 18: 974-977. 7. Kang JJ et al. De novo malignant optic chiasm glioma with initial clinical response to steroids. Neuroophthalmology 2012; 36: 59-63. 8. Thomas RP et al. The incidence and significance of multiple lesions in glioblastoma. J Neurooncol 2013; 112: 91-97
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
47th Annual Frank Walsh Society Meeting
Relation is Part of
NANOS Annual Meeting Frank B. Walsh Sessions; 2015
