| Identifier |
walsh_2019_s2_c1-abstract |
| Title |
Fire and Ice |
| Creator |
Mary Maher; Joah Aliancy; Gul Moonis; Angela Lignelli; Michael Kazim; Jeffrey Odel |
| Affiliation |
(MM) (GM) (AL) Department of Radiology, Columbia University Medical Center, New York, New York; (JA) (MK) (JO) Edward S. Harkness Eye Institute at Columbia University Medical Center, New York, New York |
| Subject |
Autoimmune Diseases; Magnetic Resonance Imaging; Optic Nerve; Retina; Demyelinating Disease |
| History |
A 14 year-old boy, with ADHD on amphetamine and dextroamphetamine, presented with headache and bilateral decreased vision. Seven days prior, he began experiencing bilateral non-positional frontal headache unresponsive to NSAIDS that did not wake him from sleep. Five days prior, he felt fatigued and noticed blurry vision and decreased color perception. He denied pain on eye movement and ocular tenderness. He was brought to medical attention when he no longer could see the food on his plate. He was camping in the Catskills one week before his headache began; he denied tick bites, fever, URI, nausea, vomiting, diarrhea and stiff neck but had a red, itchy rash on his dorsal foot. There was no history of hypertension, diabetes, heart disease, anemia or recent blood loss. He had no prior history nor a family history of headache. His acuity was HM OD and 20/500 OS, and no control AO/HRR color plates were seen. There were large dense cecocentral scotomas OU. A right RAPD was present. EOMS and saccades were intact. Slit lamp examination was unremarkable OU with normal tensions. There was disc edema and peri-papillary hemorrhages OU with a large peri-papillary cotton-wool spot OD. Retinal veins were engorged OU. MRI of the orbits showed enlarged, enhancing, tortuous orbital and pre- chiasmatic optic nerves, sparing the chiasm, with globe flattening. The brain was normal. Lumbar puncture opening pressure was 180 mm/H2O. There were 3 RBC in the CSF and 12 WBC with 95% lymphocytes, 3% monocytes, 1% neutrophils and 1% eosinophils. CSF glucose was 63, and protein was 31. The CBC revealed a WBC of 10.9 with a differential of 65% neutrophils, 26% lymphocytes, 5% monocytes, 3% eosinophils and 1% basophils. Hemoglobin was 14.3. Hematocrit was 40.1. BUN was 14. Creatinine was 0.47. AST was 33. ALT was 13. |
| Disease/Diagnosis |
Anti-myelin oligodendrocyte glycoprotein (anti-MOG) sydrome |
| Date |
2019-03 |
| References |
Biotti, et al. "Optic Neuritis in Patients with Anti-MOG Antibodies Spectrum Disorder: MRI and Clinical Features from a Large Multicentric Cohort in France." Journal of Neurology, vol. 264, no. 10, pp. 2173-2175, 2017. Chen, et al. "Myelin Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis: Clinical Characteristics, Radiologic Clues, and Outcome."American Journal of Ophthalmology, vol 195, pp 8-15, 2018. Lee and Mays. "Anti-Myelin Oligodendrocyte Glycoprotein Optic Neuritis or Neuroretinitis?" JAMA Ophthalmology, vol. 136, no. 10, 2018. Moura, Frederico Castelo, et al. "Anti-MOG (Myelin Oligodendrocyte Glycoprotein)-Positive Severe Optic Neuritis with Optic Disc Ischaemia and Macular Star." Neuro-Ophthalmology, vol. 39, no. 6, pp. 285-288, 2015. Ramanathan, Sudarshini, et al. "Radiological Differentiation of Optic Neuritis with Myelin Oligodendrocyte Glycoprotein Antibodies, Aquaporin-4 Antibodies, and Multiple Sclerosis." Multiple Sclerosis Journal, vol. 22, no. 4, pp. 470-482, 2015. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2019 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting Frank B. Walsh Sessions; 2019 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6dr7ckn |
| Setname |
ehsl_novel_fbw |
| ID |
1431957 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6dr7ckn |
