Assessing the Impact of Idebenone in Leber's Hereditary Optic Neuropathy According to Primary Mitochondrial DNA Mutation: Results From the LEROS Study

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Identifier 20230314_nanos_sciplatform3_01
Title Assessing the Impact of Idebenone in Leber's Hereditary Optic Neuropathy According to Primary Mitochondrial DNA Mutation: Results From the LEROS Study
Creator Nancy Newman; Lorena Castillo Campillo; Livia Tomasso; Patrick Yu-Wai-Man; Valerio Carelli; Thomas Klopstock
Affiliation (NN) Departments of Ophthalmology, Neurology, and Neurological Surgery, Emory University School of Medicine; (LCC) Institut Catala de Retina SL; (LTT) Chiesi Farmaceutici SpA; (PY) Department of Clinical Neurosciences, University of Cambridge; (PC) IRCCS Istituto delle Scienze Neurologiche di Bologna; (TK) Friedrich-Baur-Institut
Subject Genetic Disease; Optic Neuropathy; Retina
Description In LEROS, visual acuity (VA) outcomes following 24 months of idebenone treatment were compared to an external, matched, natural history (NH) cohort. Here, we report VA outcome results from LEROS according to primary mitochondrial DNA (mtDNA) mutation.
Date 2023-03
References None provided.
Language eng
Format video/mp4
Type Image/MovingImage
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Scientific Platform Session III: https://novel.utah.edu/collection/NAM/toc/
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s66m4ybh
Setname ehsl_novel_nam
ID 2385989
Reference URL https://collections.lib.utah.edu/ark:/87278/s66m4ybh
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