Paraneoplastic (classic) encephalitis syndromes are commonly associated with, but often present before the diagnosis of, an underlying neoplasm, most commonly small cell lung cancer (SCLC), lymphoma, thymoma or various other neoplasms. These are T-cell medicated diseases that rapidly produce neuronal dysfunction that is usually irreversible; the syndromic antibody is typically not pathogenic. In contrast, the more recently described autoimmune encephalitis syndromes are associated with pathogenic antibodies that target cell surface or synapse proteins, are less commonly associated with an underlying neoplasm, and are much more treatment-responsive than the 'paraneoplastic' category. The rate of these autoimmune encephalitidies appears to be increasing over time.
Date
2019-03
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
2019 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of
NANOS Annual Meeting 2019: New Information I Should Know
Publisher
North American Neuro-Ophthalmology Society
Holding Institution
Spencer S. Eccles Health Sciences Library, University of Utah