Characterization of Subclinical Optic Nerve MRI Lesions in the N-Momentum Trial

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Identifier 20230314_nanos_sciplatform3_06
Title Characterization of Subclinical Optic Nerve MRI Lesions in the N-Momentum Trial
Creator Jeffrey Bennett; Friedemann Paul; John Chen; Michael Smith; Daniel Cimbora; Kristina Patterson; Bruce Cree
Affiliation (JB) University of Colorado Anschutz Medical Campus; (FP) Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin Berlin, Germany, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin; (JC) Mayo Clinic; (MS) (DC) (KP) Horizon Therapeutics plc; (BC) University of California San Francisco
Subject Optic Neuritis; Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid)
Description Neuromyelitis optica spectrum disorder (NMOSD) causes inflammatory attacks on the optic nerves (ON), spinal cord, and brain. The N-Momentum trial of inebilizumab for NMOSD prospectively collected MRI data. Previously-reported subclinical MRI findings are of unknown significance.1,2 Here, we evaluate the frequency, prognosis, and response to inebilizumab of asymptomatic (subclinical) ON MRI lesions.
Date 2023-03
References 1. Paul F et al; Quiescent MRI activity in NMOSD: results from the N-MOmentum randomized placebo- controlled trial. Presented at ECTRIMS 2020 Annual Congress. 2. Shah S, et al; Frequency of Asymptomatic Optic Nerve Enhancement in a Large Retrospective Cohort of Patients With Aquaporin-4+ NMOSD. Neurology. 13;99(8):e851-e857, 2022
Language eng
Format video/mp4
Type Image/MovingImage
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Scientific Platform Session III: https://novel.utah.edu/collection/NAM/toc/
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6jz4y21
Setname ehsl_novel_nam
ID 2385994
Reference URL https://collections.lib.utah.edu/ark:/87278/s6jz4y21
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