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Vision Loss Caused by Retinal and Lateral Genlculate Nucleus Infarction in H1N1 Influenza

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Title Journal of Neuro-Ophthalmology, September 2015, Volume 35, Issue 3
Date 2015-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s62j9hxc
Setname ehsl_novel_jno
ID 227767
Reference URL https://collections.lib.utah.edu/ark:/87278/s62j9hxc

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Title Vision Loss Caused by Retinal and Lateral Genlculate Nucleus Infarction in H1N1 Influenza
Creator Dane A. Breker; Andrew W. Stacey; Ashok Srinivasan; Lulu L. C. D. Bursztyn; Jonathan D. Trobe; Mark W. Johnson
Abstract A 13-year-old girl developed encephalopathy and severe bilateral vision loss to the level of light perception within 24 hours of having fever and myalgias heralding H1N1 influenza A. Ophthalmoscopy demonstrated findings of confluent ischemic retinopathy. Brain MRI disclosed lateral geniculate body signal abnormalities indicative of hemorrhagic infarction. Despite aggressive treatment with intravenous corticosteroids, intravenous immunoglobulin, and plasmapheresis, vision did not substantially improve. This case demonstrates that H1N1 can cause simultaneous retinal and lateral geniculate body infarctions, a combination of findings not previously described in any condition. We postulate an immunologic response to the virus marked by occlusive damage to arteriolar endothelium.
Subject Adolescent; Blindness; Brain Infarction; Female; Geniculate Bodies; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Retina
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 227743
Reference URL https://collections.lib.utah.edu/ark:/87278/s62j9hxc/227743
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