Paraneoplastic Optic Neuropathy and Autoantibody Production in Small-Cell Carcinoma of the Lung

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Title Journal of Neuro-Ophthalmology, September 1998, Volume 18, Issue 3
Date 1998-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6nc968p
Setname ehsl_novel_jno
ID 224944
Reference URL https://collections.lib.utah.edu/ark:/87278/s6nc968p

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Title Paraneoplastic Optic Neuropathy and Autoantibody Production in Small-Cell Carcinoma of the Lung
Creator Luiz, JE; Lee, AG; Keltner, JL; Thirkill, CE; Lai, EC
Affiliation Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
Abstract A 59-year-old woman presented with acute-onset, bilateral, painless loss of vision, dysarthria, and ataxia. Ophthalmoscopy showed bilateral optic disc edema. A magnetic resonance scan of the head was normal. Chest radiography showed mediastinal adenopathy. Mediastinoscopy and biopsy identified small-cell carcinoma of the lung. An autoantibody to optic nerve and retina was demonstrated in the patient's serum. An electroretinogram was normal. The patient was diagnosed with a paraneoplastic optic neuropathy and paraneoplastic cerebellar syndrome. After treatment for her lung cancer, the patient remains stable from a visual and neurologic standpoint.
Subject Acute Disease; Autoantibodies/analysis; Carcinoma, Small Cell/immunology; Carcinoma, Small Cell/pathology; Electroretinography; Female; Humans; Lung Neoplasms/immunology; Lung Neoplasms/pathology; Middle Older people; Optic Nerve/immunology; Optic Nerve Diseases/diagnosis; Optic Nerve Diseases/immunology; Paraneoplastic Syndromes/diagnosis; Paraneoplastic Syndromes/immunology; Retina/immunology; Vision Disorders/diagnosis; Visual Fields
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 224933
Reference URL https://collections.lib.utah.edu/ark:/87278/s6nc968p/224933
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