Optic Nerve Head and Macular Choroidal Vascularization in Patients Affected by Normal Tension Glaucoma and Non-Arteritic Ischemic Optic Neuropathy

Two consecutive series of patients affected by chronic optic neuropathy due to NTG and N-AION, as well as a cohort of healthy subjects, underwent complete ophthalmological examination, Humphrey Visual Field (HVF), Enhanced Depth Imaging Optical Coherence Tomography (EDI OCT). Peripapillary choroidal thickness has been measured on peripapillary circular scans at 3, 6, 9, 12 clocks' hours. Macular choroidal thickness was evaluated on line scans below the subfoveal region (SF), and at 750- and 1000-μm intervals, nasally, inferiorly, temporally and superiorly to the fovea. Ganglion Cell Complex (GCC) thickness was also considered in the study. T-test and ANOVA were used to perform statistical analysis.