Posterior Cortical Atrophy - Case Report and Retrospective Review

Posterior cortical atrophy (PCA) is a rare progressive neurodegenerative disease with prominent cortical visual dysfunction, first described by Benson in 1988. Studies have shown visual field defects on formal testing, increased phosphorylated-tau protein in the CSF, and hypometabolism in the parieto-occipital regions on PET imaging. We describe one patient with PCA whose symptoms are classic but whose progression has been atypically slow. To further investigate this disease entity, we retrospectively reviewed 8 additional charts and report the commonalities in all 9 cases.