Use of low-dose beta-blockers to treat symptoms of chronic fatigue syndrome

Update Item Information
Title Use of low-dose beta-blockers to treat symptoms of chronic fatigue syndrome
Publication Type thesis
School or College School of Medicine
Department Biomedical Engineering
Author Allen, Christopher Del
Date 2014-12
Description This research explores a possible benefit to chronic fatigue syndrome and myalgic encephalomyelitis (ME/CFS) sufferers with the use of low-dose beta blockers as previous studies show potential for these treatments to lessen the symptoms of pain and fatigue in ME/CFS. Clinical data were collected from 55 patients treated with beta-adrenergic receptor-blocking agents, primarily propranolol, at the Fatigue Consultation Clinic run by Dr. Lucinda Bateman. Patient data were collected before and during treatment with the beta-blocking agents, and statistical analysis identified correlations between treatment and changes in reported measures of fatigue, body aches, pain, headaches, inactivity/function, hours spent vertical in a 24 hour period, and hours spent horizontal in a 24 hour period. After performing statistical analysis on the data, no correlations between the treatment and symptom severity were apparent. However, the subjective nature of the clinical data and the potential for confounding variables warrant a more complete clinical trial.
Type Text
Publisher University of Utah
Subject MESH Signs and Symptoms; Fatigue Syndrome, Chronic; Mitochondrial Diseases; Fibromyalgia; Adrenergic beta-Antagonists; Propranolol; Depression; Anxiety; Severity of Illness Index; Surveys and Questionnaires
Dissertation Institution University of Utah
Dissertation Name Master of Science
Language eng
Relation is Version of Digital reproduction of Use of Low-Dose Beta-Blockers to Treat Symptoms of Chronic Fatigue Syndrome
Rights Management Copyright © Christopher Del Allen 2014
Format application/pdf
Format Medium application/pdf
Format Extent 1,515,941 bytes
Source Original in Marriott Library Special Collections
ARK ark:/87278/s6n34bp2
Setname ir_etd
ID 1423038
Reference URL https://collections.lib.utah.edu/ark:/87278/s6n34bp2
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