Ocular Myasthenia: How do I Treat?

Myasthenia gravis is caused by pathogenic autoantibodies to the postsynaptic neuromuscular junction. Clinically, this may affect any of the skeletal muscles causing variable weakness, which worsens with continued muscle activity. Ocular myasthenia gravis (OMG) may affect the levator palpebrae superioris, extraocular muscles, and orbicularis oculi causing ptosis and diplopia. Meanwhile, generalized myasthenia gravis (GMG) refers to involvement of the non-ocular skeletal muscles. This talk will focus on treatment strategies for OMG. Discussion of the diagnosis of OMG and the treatment of GMG is beyond the scope.