Identifier |
20220215_nanos_sciplatform3_01 |
Title |
Sustainability of Teprotumumab Efficacy in Thyroid Eye Disease |
Creator |
Prem S. Subramanian; Saba Sile; Robert Holt; Raymond Douglas |
Affiliation |
(PSS) University of Colorado, Aurora, CO; (SS) (RH) Horizon Therapeutics plc, Deerfield, IL; (RSD) Cedars Sinai Medical Center Los Angeles; Shanghai International Medical Center |
Subject |
Neuro-ophth & Systemic Disease (eg. MS, MG, Thyroid); Graves' Disease |
Description |
Teprotumumab, an insulin-like growth factor-I receptor inhibitory antibody, improved proptosis, diplopia, inflammatory signs/symptoms, and quality of life in thyroid eye disease (TED) patients in phase 2 and 3 (OPTIC) trials.1,2 OPTIC proptosis non- responders could receive a course of teprotumumab in the OPTIC-X study. This analysis examined sustainability of response over the follow-up periods from the phase 2, OPTIC and OPTIC-X studies, including the recently proposed EUGOGO composite outcome. |
Date |
2022-02 |
Language |
eng |
Format |
video/mp4 |
Type |
Image/MovingImage |
Source |
2022 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2022: Scientific Platform III |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2022. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6a7xdfv |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
2187015 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6a7xdfv |