Role of the Spike Glycoprotein in Viral-Induced Experimental Optic Neuritis

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Identifier 20090224_nanos_posters_094.pdf
Title Role of the Spike Glycoprotein in Viral-Induced Experimental Optic Neuritis
Creator Kenneth S. Shindler; Mahasweta Dutt; Jayasri Das Sarma
Affiliation (KSS) (MD) University of Pennsylvania, Philadelphia, PA; Thomas Jefferson University, Philadelphia, PA; (JDS) IISER-Kolkata, Kolkata, India
Subject Optic Neuritis; Multiple Sclerosis; Demyelination; Animal Models; Mouse Hepatitis Virus
Description Infection of mice with neurovirulent strains of mouse hepatitis virus (MHV) is used as a model for virus induced demyelination that mimics many pathologic features of multiple sclerosis. A significant incidence of optic neuritis occurs in mice infected with a demyelinating strain of MHV (MHV-A59), but not with the nondemyelinating strain, MHV-2. Mechanisms underlying this differential induction of optic neuritis are not known.
Date 2009-02-24
Language eng
Format application/pdf
Type Text
Source 2009 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2009: Poster Presentations
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s64t9qr0
Setname ehsl_novel_nam
ID 180500
Reference URL https://collections.lib.utah.edu/ark:/87278/s64t9qr0
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