Identifier |
20090224_nanos_posters_094.pdf |
Title |
Role of the Spike Glycoprotein in Viral-Induced Experimental Optic Neuritis |
Creator |
Kenneth S. Shindler; Mahasweta Dutt; Jayasri Das Sarma |
Affiliation |
(KSS) (MD) University of Pennsylvania, Philadelphia, PA; Thomas Jefferson University, Philadelphia, PA; (JDS) IISER-Kolkata, Kolkata, India |
Subject |
Optic Neuritis; Multiple Sclerosis; Demyelination; Animal Models; Mouse Hepatitis Virus |
Description |
Infection of mice with neurovirulent strains of mouse hepatitis virus (MHV) is used as a model for virus induced demyelination that mimics many pathologic features of multiple sclerosis. A significant incidence of optic neuritis occurs in mice infected with a demyelinating strain of MHV (MHV-A59), but not with the nondemyelinating strain, MHV-2. Mechanisms underlying this differential induction of optic neuritis are not known. |
Date |
2009-02-24 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2009 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2009: Poster Presentations |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s64t9qr0 |
Setname |
ehsl_novel_nam |
ID |
180500 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s64t9qr0 |