Title |
Neutrophilic myelocyte |
Creator |
Poels, Lambert G. |
Contributor |
Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen |
Date |
2007-12-01 |
Subject |
Blood; Bone Marrow; Electron microscopy; Neutrophilic myelocyte; Neutrophilic granulocyte; Primary granule; Secondary granule; Azurophilic granule; Lysosome |
Description |
Scheme electron microscopy. From CFU-S (colony forming units-spleen) stem cells arise CFU-GM (colony forming unit-granulocyte/monocyte) stem cells. The latter divide by mitoses and differentiate via promyeloblasts and myeloblasts into myelocytes (the last proliferative stage). The neutrophilic myelocyte (10-15 μm) contains a large nucleus (nucleoli disappear) and well developed organelles, a distinct Golgi area and specific or secondary granules. The primary ('non-specific' or azurophilic) granules (0.3-0.4 μm) are electron-grey (1) and contain among others acid phosphatase and arylsulfatase. The secondary (specific) electron-dense granules (2) contain lysosome and phagocytin. |
Subtype |
Image |
Format |
image/jpeg |
Rights |
http://creativecommons.org/licenses/by-nc-nd/3.0/ |
Collection |
Poja Histology Collection - Blood & Bone Marrow Subset |
ARK |
ark:/87278/s6h44trv |
Setname |
ehsl_heal |
ID |
891049 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6h44trv |