Acute Management of Optic Neuritis - An Evolving Paradigm

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Title Acute Management of Optic Neuritis - An Evolving Paradigm
Creator Lindsay Horton, MD; Jeffrey L. Bennett, MD, PhD
Affiliation Departments of Neurology (LH, JLB) and Ophthalmology (JLB), University of Colorado Denver, Aurora, Colorado; and Program in Neuroscience (JLB), University of Colorado Denver, Aurora, Colorado
Abstract The current management of acute optic neuritis (ON) is focused on expediting visual recovery through the use of high-dose intravenous corticosteroids. The recent identification of specific autoantibodies associated with central nervous system inflammatory disorders has provided novel insights into immune targets and mechanisms that impact the prognosis, treatment, and recurrence of ON. Therefore, neurologists and ophthalmologists need to be aware of clinical, laboratory, and imaging findings that may provide important clues to the etiology of ON and the potential need for aggressive management. Moving forward, rapid and accurate diagnosis of inflammatory ON will likely be critical for implementing clinical care that optimizes short-term and long-term therapeutic outcomes.
Subject Acute Disease; Disease Management; Dose-Response Relationship, Drug; Glucocorticoids / administration & dosage; Humans; Immunotherapy / methods; Optic Nerve / pathology; Optic Neuritis / diagnosis; Optic Neuritis / therapy; Prognosis; Tomography, Optical Coherence / methods
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Date 2018-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, September 2018, Volume 38, Issue 3
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6f81dgx
Setname ehsl_novel_jno
ID 1500791
Reference URL https://collections.lib.utah.edu/ark:/87278/s6f81dgx
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