Walsh & Hoyt: Laboratory Tests

Patients with MFS can demonstrate changes in the CSF identical with AIDP. There is increased concentration of CSF protein, usually without pleocytosis. Electrophysiologic studies tend to be abnormal. Electromyography (EMG) reveals evidence of demyelination, occasionally associated with evidence of axonal degeneration. Detailed EMG and nerve conduction studies usually show abnormal conduction in peripheral sensory fibers from the initial stages of the disease. Abnormal brainstem auditory evoked potentials (BAEPs) have been reported in some patients.