Pyrogenic and emetic effects of staphylococcal enterotoxin

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Title Pyrogenic and emetic effects of staphylococcal enterotoxin
Publication Type thesis
School or College College of Pharmacy
Department Pharmacology & Toxicology
Author Clark, Wesley Gleason
Date 1962-08
Description Endotoxins are high molecular weight lipopolysaccharides, derived primarily from gram-negative bacteria. They produce a wide variety of effects in animals and man including fever, alterations of blood leukocyte counts and glucose levels, the Shwartzman reaction, tumor necrotizing effects and cardiovascular effects. Endotoxins are responsible for various so-called " injection fevers" which have been of interest since the late 1800's and which are caused by contamination of solutions by gram-negative bacteria. The possibility of such contamination must be taken into account in any study of pyrogenic effect supposedly induced by another agent. Recent reviews discussing various physiological effects of endotoxin include those by Bennett and Cluff (1957), Gilbert (1960) and Atkins (1960). The present survey will consider only those aspects of the pyrogenic effect and changed in leukocyte counts which are important for a comparison with enterotoxin and for an understanding of some of the pyrogenic agents.
Type Text
Publisher University of Utah
Subject Enterotoxins; Staphylococcal infections
Subject MESH Enterotoxins; Staphylococcal Food Poisoning
Dissertation Institution University of Utah
Dissertation Name PhD
Language eng
Relation is Version of Digital reproduction of "The Pyrogenic and emetic effects of staphylococcal enterotoxin". Spencer S. Eccles Health Sciences Library.
Rights Management © Wesley Gleason Clark.
Format application/pdf
Format Medium application/pdf
Format Extent 1,766,098 bytes
Identifier undthes,4267
Source Original: University of Utah Spencer S. Eccles Health Sciences Library (no longer available).
Master File Extent 1,766,142 bytes
ARK ark:/87278/s6kp841t
Setname ir_etd
ID 191446
Reference URL https://collections.lib.utah.edu/ark:/87278/s6kp841t
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