Role of autonomous activity of the uterus in determining drug responses and the interrelations of drugs in producing uterine responses

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Title Role of autonomous activity of the uterus in determining drug responses and the interrelations of drugs in producing uterine responses
Publication Type thesis
School or College College of Pharmacy
Department Pharmacology & Toxicology
Author Daniel, Edwin E.
Date 1952
Description There seem to be at least two possible viewpoints with which a thesis problem may be attacked. First, and perhaps more common, is the viewpoint that some limited aspects must be studied exhaustively. The second viewpoint is that a problem should be surveyed in order that the approaches for postdoctoral work may be uncovered. There are certain advantages to each approach. However, in the study undertaken here, the nature of the problem itself tended to force the adoption of the second point of view. Thus the question of an explanation for the finding that certain drugs diminished contractions induced by subsequent drugs was the starting point. However, the state of knowledge of smooth muscle physiology and pharmacology did not seem to allow even a place for this finding, much less offer of ready explanation. Therefore, it became necessary to examine critically many of the dogmas concerning smooth muscle. In the course of these reexaminations many unusual results were obtained, each leading to further reexaminations of accepted theories until finally the greatest difficulty became the finding of a convenient stopping point. Almost inevitable when a problem progresses in this manner, many loose ends remain. However, it seems that the overall picture which appeared will be of aid not only in eventually trying together these loose ends, but also in elucidating the mechanisms of inducing contractions of smooth muscle.
Type Text
Publisher University of Utah
Subject MESH Uterus; Physiology
Dissertation Institution University of Utah
Dissertation Name PhD
Language eng
Relation is Version of Digital reproduction of "The Role of autonomous activity of the uterus in determining drug responses and the interrelations of drugs in producing uterine responses Spencer S. Eccles Health Sciences Library.
Rights Management © Edwin E. Daniel.
Format application/pdf
Format Medium application/pdf
Format Extent 9,937,791 bytes
Identifier undthes,3940
Source Original University of Utah Spencer S. Eccles Health Sciences Library (no longer available)
Master File Extent 9,937,810 bytes
ARK ark:/87278/s6bg2qs6
Setname ir_etd
ID 190820
Reference URL https://collections.lib.utah.edu/ark:/87278/s6bg2qs6
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