NOVEL - NANOS Annual Meeting

Amnion-derived Multipotent Progenitor Cells Attenuate Optic Nerve and Spinal Cord Demyelinating Disease

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Identifier 20190319_nanos_sciplatform3_03-video
Title Amnion-derived Multipotent Progenitor Cells Attenuate Optic Nerve and Spinal Cord Demyelinating Disease
Creator Kenneth Shindler; Reas Khan; Kimberly Dine; Ahmara Ross; Keirnan Willett; Rick Banas; Larry Brown
Affiliation (KS) (RK) (KD) (AR) (KW) University of Pennsylvania, Philadelphia; (RB) (LB) Noveome Biotherapeutics, Inc., Pittsburgh
Subject Neuro-Ophth & Systyemic Disease (eg. MS, MG, Thyroid); Optic Neuropathy; Demeylinating Disease
Description ST266 is the biological secretome of Amnion-derived Multipotent Progenitor (AMP) cells. ST266 proteins accumulate in eyes and optic nerves following intranasal delivery, resulting in selective suppression of optic neuritis in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis, without suppressing spinal cord lesions. We tested the hypothesis that systemic AMP cell administration could suppress both optic neuritis and myelitis in EAE.
Date 2019-03
Language eng
Format video/mp4
Type Image/MovingImage
Source 2019 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2019: Scientific Platform III
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6dn8nd2
Setname ehsl_novel_nam
ID 1427560
Reference URL https://collections.lib.utah.edu/ark:/87278/s6dn8nd2
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