Identifier |
walsh_2009_s4_c2_pp |
Title |
Hear No Evil, See No Evil (PowerPoint) |
Creator |
Sashank Prasad, MD, Neuro-Ophthalmology Fellow, University of Pennsylvania, Philadelphia, PA |
Affiliation |
Hospital of the University of Pennsylvania, Philadelphia |
Subject |
Mitochondrial Encephalomyopathies; MELAS Syndrome; Point Mutation; Hearing Loss, Sensorineural; Scotoma; Pupil Disorders; Optic Neuritis |
History |
A 62-year old female with painless loss of vision OS. Previous history significant for bilateral sensorineural deafness. |
Pathology |
Retinal nerve fiber atrophy; Axonal polyneuropathy; Inherited mitochondrial disorder |
Disease/Diagnosis |
MELAS Syndrome |
Clinical |
VA: 20/20 OD, 20/200 OS; Color plates: 8/11 OD, 0/11 OS; RAPD OS |
Presenting Symptom |
Painless loss of vision OS |
Neuroimaging |
MRI |
Treatment |
N/A |
Date |
2009-02 |
References |
1. Dickerson, Holtzman, Grant, Tian. Case records of the Massachusetts General Hospital. Case 36-2005. A 61-year-old woman with seizure, disturbed gait, and altered mental status. N Engl J Med 353, 2271-2280, 2005. 2. Mizrachi, Gomez-Hassan, Blaivas, Trobe. Pitfalls in the diagnosis of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes. J Neuroophthalmol, 26, 38-43, 2006. 3. Apostolova, White, Moore, et al. Deep white matter pathologic features in watershed regions. A novel pattern of central nervous system involvement in MELAS. Arch Neurol 62, 1 1 54-6, 2005. 4. Goto, Nonaka, Horai. A mutation in the tRNA(Leu) (UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature, 348, 651-653, 1990. 5. Scaglia, Northrop. The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options. CNS Drugs 20, 443-464, 2006. |
Language |
eng |
Format |
application/pdf |
Format Creation |
Microsoft PowerPoint |
Type |
Text |
Source |
41st Annual Frank Walsh Society Meeting |
Relation is Part of |
Session 4, Case 2, Walsh Session, NANOS 2009 |
Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2002. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s69c718r |
Setname |
ehsl_novel_fbw |
ID |
178722 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s69c718r |