Cuban Epidemic Optic Neuropathy: A Mitochondrial Insufficency?

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Identifier 19940303_nanos_opticneuropathysympos_05
Title Cuban Epidemic Optic Neuropathy: A Mitochondrial Insufficency?
Creator Alfredo A. Sadun; Larry P. Frohman; Richard L. Sogg
Affiliation (AAS) Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC
Subject Optic Neuropathy; Mitochondrial Insufficiency; Cuba; Leber's Hereditary Optic Neuropathy; Epidemiology
Description In January of 1992, in a remote western province of Cuba (Pinar del Rio), men between the ages of 25 and 64 began presenting with visual and neurological complaints . Most patients suffered a sub-acute loss of vision in both eyes. Additionally, approximately 20% of the patients complained ofparesthesias or dysesthesias.' Additionally, many patients had considerable weight loss as well as fatigue and polyuria. While the ftrst few cases were diagnosed as tobacco/alcohol amblyopia, by mid 1992 the number of cases had reached epidemic proportions.' When coxsackie virus grew out from most samples of cerebral spinal fluid (CSF), a viral hypothesis came into favor.' By the end of 1992, nearly 1000 cases bad been diagnosed, still mainly from the rural western area of Cuba.
Date 1994-03-03
Language eng
Format application/pdf
Type Text
Source 1994 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 1994: Clinical Presentations (Session III)
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 1994. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6sn3gm6
Setname ehsl_novel_nam
ID 182817
Reference URL https://collections.lib.utah.edu/ark:/87278/s6sn3gm6
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