| Identifier |
walsh_2017_s3_c3-slideshow |
| Title |
Island Fever (slideshow) |
| Creator |
Laura Hanson, Judith E. A. Warner, MD, Moran Eye Center, University of Utah, Alison Crum, Bradley Katz, Kathleen B. Digre, MD, Professor of Neurology and Ophthalmology, Director of Neuro-Ophthalmology, John A. Moran Eye Center, University of Utah School of Medicine |
| Subject |
Meningitis, Increased intracranial pressure, 6th nerve palsy |
| History |
A 22 year-old male paralegal in the military presented with double and blurred vision. One month ago, he had traveled to Hawai'i for a wedding. Two weeks ago, he had been evaluated for an acute onset of fever, headache, emesis, light sensitivity and neck stiffness. |
| Disease/Diagnosis |
Eosinophilic Meningitis secondary to Angiostrongylus cantonensis. Angiostrongylus cantonensis is also known as the "Rat Lungworm" and was first found in the lungs of rats in South China. The nematode larvae live in the pulmonary veins of their definitive host, the rat, and are perpetuated by snails, which serve as a secondary host. It is endemic in Southeast Asia, the Pacific Basin, the Caribbean, and Hawai'i. Humans become infected by eating undercooked snails, freshwater shrimp, frogs, or unwashed produce contaminated by one of these hosts. The larvae migrate to the central nervous system and the induced inflammatory response creates the manifestations typically seen in humans, including meningitis, cranial nerve abnormalities, ataxia, encephalitis, and increased intracranial pressure. The larvae are presumed to die before reaching the lungs. Treatment generally includes high- dose systemic corticosteroids. Albendazole can be used in combination with steroids, but there is some concern that the rapid death of the larvae from the anthelmintic can worsen the inflammatory response. |
| Date |
2017-04 |
| References |
H. T.Chen. Un nouveau nematode pulmonaire: Pulmomema cantonensis n.g.n.spp. de rats de Canton. Annales de Parasitologie Humaine et Comparée 13, 312-317, 1935. Yii CY. Clinical observations on eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis on Taiwan. Am J Trop Med Hyg. 25(2):233-249, 1976. Murphy GS, Johnson S. Clinical aspects of eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis, the rat lungworm. Hawaii J Med Public Health. 72(6 Suppl 2),35-40, 2013. Kwon E, Ferguson TM, Park SY, et al. A Severe Case of Angiostrongylus Eosinophilic Meningitis with Encephalitis and Neurologic Sequelae in Hawai‘i. Hawaii J Med Public Health. 72(6 Suppl 2),41-45, 2013. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
49th Annual Frank Walsh Society Meeting |
| Relation is Part of |
NANOS Annual Meeting 2017: Frank B. Walsh Session 3 |
| Collection |
Neuro-Ophthalmology Virtual Education Library - Walsh Session Annual Meeting Archives https://novel.utah.edu/Walsh/index3.html |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-6120 |
| Rights Management |
Copyright 2017. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6wx1cb9 |
| Setname |
ehsl_novel_fbw |
| ID |
1277714 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6wx1cb9 |
