Small Surprises Along the Journey (Presentation Video)
Creator
Janet Rucker, MD
Affiliation
Chicago, IL
Subject
Ovarian Neoplasms; Carcinoma; Pathologic Nystagmus; Autoimmune Diseases of the Nervous System; Paraneoplastic Cerebellar Degeneration
History
29-year old female with a 2-year history oscillopsia. Previous history significant for Dx ovarian cancer three years before Tx surgery and chemotherapy.
Pathology
Primary ovarian undifferentiated small cell carcinoma
Disease/Diagnosis
Paraneoplastic cerebellar degeneration with anti-Hu antibodies in the CSF secondary to recurrent small cell ovarian cancer.
Clinical
VA: 20/40 OD, 20/30 OS; Normal color vision
Presenting Symptom
Visual distortions; Gait disturbances
Neuroimaging
MRI
Treatment
Antineoplastic agents; IVIG
Date
2007-02
References
1. Eichhorn JH, Young RH, Scully RE. Primary ovarian small cell carcinoma of pulmonary type: a clinicopathologic, immunohistologic, and flow cytometric analysis of 11 cases. Am J Surg Pathol 16, 926-938, 1992. 2. Pittock SJ, Kryzer TJ, Lennon VA. Paraneoplastic antibodies coexist and predict cancer, not neurological syndrome. Ann Neurol 56, 715-719, 2004.
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
39th Annual Frank Walsh Society Meeting
Relation is Part of
NANOS Annual Meeting Frank B. Walsh Sessions; 2007
