Title |
A Diagnostic Quartet in Leptomeningeal Infiltration of the Optic Nerve Sheath |
Creator |
Robert McFadzean, FRCSEd; Donal Brosnahan, FRCSEd; David Doyle, MD; James Going, MRCPath; Donald Hadley, FRCR; William Lee, MD |
Affiliation |
Department of Neuro-ophthalmology, Tennent Institute, University of Glasgow, Scotland |
Abstract |
A rare case of optic leptomeningeal carcinomatosis secondary to a rectal adenocarcinoma is recorded. The presentation of rectal disease with blindness is unique. A diagnostic quartet of symptoms and signs of leptomeningeal infiltration of the optic nerve sheath is proposed and its value emphasized by the inability of further investigation to confirm the clinical diagnosis. The investigation and treatment of leptomeningeal carcinomatosis is reviewed. |
Subject |
Adenocarcinoma/Secondary; Adult; Blindness/Diagnosis; Cranial Nerve; Neoplasms/Secondary; Humans; Male; Meningeal Neoplasms/Radiography; Meningeal Neoplasms/Secondary; Myelin Sheath/Pathology; Optic Nerve Diseases/Pathology; Pupil Disorders/Diagnosis; Rectal Neoplasms/Pathology; Subarachnoid Space |
Date |
1996-09 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
ARK |
ark:/87278/s6dc16x0 |
Setname |
ehsl_novel_jno |
ID |
224510 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6dc16x0 |