Identifier |
19920223_nanos_geneticsnosympos_03 |
Title |
Intracerebral Grafting of Genetically Modified Cells |
Creator |
Fred H. Gage, PhD |
Affiliation |
La Jolla, California |
Subject |
Intracerebral Grafting; Genetically Modified Cells; Transgene; Brain Function; Trophic Molecules; Neurotransmitters; Synaptically Mediated Neurotransmittersl Regenerating Axons |
Description |
The rationale for implanting cells to the brain is either for potential clinical application or to understand basic principals of brain function. The expectation of how an implanted cell would function differs for each experimental paradigm, and in many cases the mechanism of action is unknown. Among the possible mechanisms of action for implanted cells are: 1) to deliver trophic or tropic molecules; 2) to provide for secretion of neurotransmitters or hormones; 3) to release synaptically mediated neurotransmitters, and 4) to act as a bridge for regenerating axons to grow from the proximal side of a lesion to the distal side. |
Date |
1992-02-23 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
1992 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 1992: Genetics in Neuro-Ophthalmology |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 1992. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6s21858 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
182941 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6s21858 |