| Identifier |
walsh_2000_s6_c4 |
| Title |
Multiple Intracranial Lesions Following Treatment of Nelson's Symptoms |
| Creator |
Luis J. Mejico, MD; Pierre Krolak-Salmon, MD; Neil R. Miller, MD |
| Affiliation |
(LJM) (PKS) (NRM) Johns Hopkins Wilmer Eye Institute, Baltimore, MD |
| Subject |
Adrenalectomy; Nelson Syndrome; Cushing Syndrome; Pituitary Neoplasms; Oculomotor Nerve Diseases; Trochlear Nerve Diseases; Abducens Nerve Diseases; Ocular Motility Disorders; Pupil Disorders; Blepharoptosis |
| History |
A 75-year old female with no light perception OD and right third, fourth and sixth nerve pareses. Previous history significant for diabetes mellitus, hypertension, Cushing syndrome and Nelson syndrome. After CD Dx, a bilateral adrenalectomy was performed. |
| Pathology |
Pituitary carcinoma |
| Disease/Diagnosis |
Nelson Syndrome |
| Clinical |
VA: NLP OD, 20/40 OS; Color plates: Unable to identify OS, Colors of large objects OD; RAPD OD |
| Presenting Symptom |
Cognitive decline; Alexia with agraphia |
| Neuroimaging |
MRI |
| Treatment |
Surgery; XRT |
| Date |
2000 |
| References |
1. Grua JR and Nelson DH: ACTH-Producing Pituitary Tumors. Endocrinol Metab Clin North Am 1991; 20: 319-62. 2. Pernicone PJ, Bernd WS, Sebo TJ, et al: Pituitary Carcinoma Cancer 1997; 79(4): 804-12. 3. Kemink SA, Wesseling P, Pieters GF, et al: Progression of a Nelson's Adenoma to Pituitary Carcinoma; a case report and review of the literature. J Endocrinol Invest 1999; 22(1): 70-5. 4. Kemink L, Picters G, Hermus A, Smals A, Kloppenborg P: Patient's Age is a Simple Predictive Factor for the development of Nelson's Syndrome after Total Adrenalectomy for Cushing's Disease. J Clin Endocrinol Metab 1994; 79(3): 887-9. 5. Frost AR, Tenner S, Tenner M, Rollhauser C, Tabbara SO: ACTH-Producing Pituitary Carcinoma Presenting as the Cauda Equina Syndrome. Arch Pathol Lab Med 1995; 199(1): 93-6. 6. Lormeau B, Miossec P, Sibony M, Valensi P, Attali JR: Adrenocorticotropin-Producing Pituitary Carcinoma with Liver Metastatis. J Endocrinol Invest 1997; 20(4): 230-6. 7. Buchfelder M, Fahlbusch R, Thierauf P, Muller OA: Observations on the Pathophysiology of Nelson's Syndrome: A Report of Three Cases. Neurosurgery 1990; 27(6): 961-8. 8. Saegler W, Geisler F, Ludecke DK: Pituitary Pathology in Cushing's Disease. Path Res Pract 1988; 183: 592-5. 9. Favia G, Boscaro M, Lumachi F, D'Amico DF: Role of Bilateral Adrenaletomy in Cushing's Disease. World J Surg 1994; 18:462-6. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
26th Annual North American Neuro-Ophthalmology Society Meeting, Frank B. Walsh Session CD-ROM |
| Relation is Part of |
NANOS Annual Meeting Frank B. Walsh Sessions; 2000 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6qj7m13 |
| Setname |
ehsl_novel_fbw |
| ID |
177728 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6qj7m13 |
