| Description |
In 1977, powerful DNA sequencing techniques were announced by Walter Gilbert and Frederick Sanger. The concurrent development of these two important DNA sequencing techniques has fostered the rapid accumulation of sequence data currently, there are almost ten million bases of information available for analysis. The rapid development of sequencing techniques required the development of computer programs capable of manipulating, analyzing, and comparing long sequences of data. The proliferation of such software is all too obvious: programs are now available which aid in planning cloning projects [3], predict secondary structure of tRNA and mRNA [4], determine whether a sequence is protein-coding or noncoding [5, 6], and search for such signals as promoters [6, 7]. |
