Slit Ventricle Syndrome

Update Item Information
Identifier Slit_Ventricle_Syndrome_Lee
Title Slit Ventricle Syndrome
Creator Andrew G. Lee, MD
Affiliation (AGL) Chairman, Department of Ophthalmology, The Methodist Hospital, Houston, Texas; Professor of Ophthalmology, Weill Cornell Medicine, New York City, New York; () Class of , Baylor College of Medicine, Houston, Texas
Subject Hydrocephalus; Shunt; Laplace; ICP
Description Dr. Lee lectures medical students on slit ventricle syndrome.
Transcript "So today, I want to talk to you about the slit ventricle syndrome, and you don't have to know everything about slit ventricles. But you have to know a little bit in neuro-ophthalmology because it comes to us. So, the slit ventricle syndrome is the opposite of ventriculomegaly and hydrocephalus. So, when you have a scan and you have big ventricles, that's hydrocephalus. That can be obstructive or communicating or non-commuting hydrocephalus. When we see hydrocephalus, the things that are going to come to us are papilledema (the swollen disc from increased ICP), the dorsal midbrain syndrome, and the non-localizing sixth nerve palsy. They're going to have symptoms of increasing intracranial pressure: headache, tinnitus, double vision, loss of vision, and normally the hydrocephalus cases are pretty straightforward. If they already have a shunt in place, it's shunt failure until proven otherwise. So, the normal scenario that we see is: big ventricles, shunt failure or needs a shunt, signs and symptoms of increased intracranial pressure. However, sometimes the ventricle is not big, it's small. This is called the slit ventricle syndrome, and the slit ventricle is usually because they already have a shunt in place and the ventricle has collapsed. In this setting, the slit ventricle syndrome that's normally from chronically shunted hydrocephalus, previous hydrocephalus that they shunted, and we're going to be looking for the same symptoms and signs of increased intracranial pressure. Normally, you'd expect if they've got a shunt in place that it would be over-draining and that we'd have too low of an intracranial pressure. So, we have competing hypotheses with the slit ventricle. Normally, it's over-drainage and your ICP is too low. But sometimes, the pressure is still too high and the reason is that the compliance has been lost here in the ventricle; it can no longer expand. Or, the law that you're familiar with already on the other videos, and you can re-watch those, the law of Laplace. So, in the law of Laplace, the tension equals the pressure times the radius. And you know that if you've ever tried to blow up a balloon when it's flat it's hard because the radius is so small. So, the amount of P, pressure, necessary to blow up a flat balloon is a lot higher to overcome the elasticity of that balloon. In order to generate enough T so that the balloon will expand, just like the ventricle has to expand to make the radius go up, we have to use a lot of P, air pressure, at the beginning of blowing up the balloon. What that means for you is if the ventricle is already slit, that means the radius is already small, and that means the amount of P (intracranial pressure) to generate sufficient T (wall tension) to expand is going to be greater. And that means there's a competing hypothesis on the slit ventricle. It doesn't have to be over-drainage, it could actually be under-drainage; your pressure is actually high but insufficient to generate enough P to get this T to go up because the R is so small. That means shunt failure, and so we cannot rely upon the CT scan alone to tell us what the function of the shunt is. And, especially in the setting of a slit ventricle, you're going to do a shunt series, which is a series of x-rays to make sure it's not disconnected. But, if it is connected, and you still think it's failed, the only way to know is to put dye into the shunt called a shuntogram - technetium is normally what we use to see if the shunt is broken. And the only way to measure the pressure is to have a spinal tap. So, you need to know that the big ventricle syndrome is easy, and the bigger ventricle syndrome is hydrocephalus or shunt malfunction. But the slit ventricle is hard. The reason it's hard is that it could be too much drainage, or it could be too little drainage. And, if it's too little drainage, it's because of the law of Laplace."
Date 2022-03
Language eng
Format video/mp4
Type Image/MovingImage
Collection Neuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6fsyqnd
Setname ehsl_novel_lee
ID 1751094
Reference URL https://collections.lib.utah.edu/ark:/87278/s6fsyqnd
Back to Search Results