An Insidious Mimicker Causing Mixed Neurologic Symptoms

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Identifier 20230312_nanos_posters_064
Title An Insidious Mimicker Causing Mixed Neurologic Symptoms
Creator Taylor Campbell; Aroucha Vickers; Trusha Mehta; Robert Balsiger
Affiliation (TC) (TM) (RB) Valley Hospital Medical Center; (AV) Las Vegas Neurology Center
Subject Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid); High Intracranial Pressure/Headache; Tumors; Miscellaneous
Description Chronic lymphocytic leukemia (CLL) is a B cell lympho proliferative disorder that most often presents asymptomatically, but can rarely cause neurologic and Neuro-ophthalmic complications. It may be mistaken for other great mimickers such as systemic lupus erythematosus and neurosarcoidosis. Neurologic manifestations are associated with transformation into a more aggressive form of CLL.
Date 2023-03-14
References 1. Hallek M, Cheson BD, Catovsky D, et al. Guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL. Blood. 2018;131(25):2745. 2. Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer Statistics, 2022. CA Cancer J Clin. 2022;72(1):7. 3. Delestre F, Blanche P, Bouayed E, et al. Ophthalmic involvement of chronic lymphocytic leukemia: a systematic review of 123 cases. Surv Ophthalmol. 2021 Jan-Feb;66(1):124-131. 4. Sáenz-Francés F, Calvo-González C, Reche-Frutos J, et al. [Bilateral papilledema secondary to chronic lymphocytic leukaemia]. Arch Soc Esp Oftalmol. 2007 May;82(5):303-6. Spanish. 5. Mitsui Y, Kusunoki S, Hiruma S, et al. Sensorimotor polyneuropathy associated with chronic lymphocytic leukemia, IgM antigangliosides antibody and human T-cell leukemia virus I infection. Muscle Nerve. 1999 Oct;22(10):1461-5. 6. Aki Z, Aksoy O, Sucak G, et al. Miller-Fisher syndrome associated with chronic lymphocytic leukemia. Neurol India. 2008 Apr-Jun;56(2):198-200. 7. Burns TM. Neurosarcoidosis. Arch Neurol. 2003;60(8):1166-1168. 8. Stern BJ, Krumholz A, Johns C, Scott P, Nissim J. Sarcoidosis and Its Neurological Manifestations. Arch Neurol. 1985;42(9):909-917. 9. Henderson AD, Tian J, Carey AR. Neuro-Ophthalmic Manifestations of Sarcoidosis. J Neuroophthalmol. 2021 Dec 1;41(4):e591-e597. 10. Gonsalves WI, Zent CS, Pulido JS, Patnaik MM. Visual loss in early-stage chronic lymphocytic leukemia. J Clin Oncol. 2013 Jun 10;31(17):e280-2. 11. Khan K, Malik AI, Almarzouqi SJ,et al. Optic neuropathy due to chronic lymphocytic leukemia proven with optic nerve sheath biopsy. J Neuroophthalmol. 2016 Mar;36(1):61-6.
Language eng
Format application/pdf
Type Text
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Poster Session I: Neuro-Ophthalmic Disorders of Neurologic and Systemic Diseases
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6ekfa4e
Setname ehsl_novel_nam
ID 2335270
Reference URL https://collections.lib.utah.edu/ark:/87278/s6ekfa4e
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