Mechanisms of Interrupted Saccades Differ in Normal Subjects and Late Onset Tay-Sachs Patients

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Identifier 20070213_nanos_posters_074.pdf
Title Mechanisms of Interrupted Saccades Differ in Normal Subjects and Late Onset Tay-Sachs Patients
Creator Janet C. Rucker; Ed Keller; Lance Optican; R. John Leigh
Affiliation (JCR) Rush University, Chicago, IL; (EK) Smith Kettlewell Eye Institute, San Francisco, CA; (LO) National Eye Institute, NIH, Bethesda, MD; (RJL) Case University, Cleveland, OH
Subject Saccades; Ocular Motility; Late Onset Tay Sachs
Description Saccades normally occur in one smooth movement. In late-onset Tay-Sachs disease (LOTS), saccades have initial normal acceleration, but are interrupted by a transient deceleration greater than that at normal saccade end. Before eye velocity reaches zero, it reaccelerates and goes to target. These saccades are similar to those seen when monkey omnipause neurons are stimulated at saccade onset. Two-step saccades are occasionally seen in normal subjects.
Date 2007-02-13
Language eng
Format application/pdf
Type Text
Source 2007 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2007: Poster Presentations
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6vq683f
Setname ehsl_novel_nam
ID 181400
Reference URL https://collections.lib.utah.edu/ark:/87278/s6vq683f
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