The Relationship Between PDE-5 Inhibitors and NAION

Update Item Information
Identifier 20150223_nanos_journalclub1_02
Title The Relationship Between PDE-5 Inhibitors and NAION
Creator Howard D. Pomeranz, MD
Subject Erectile Dysfunction Drug; Non-Arteritic Anterior Ischemic Optic Neuropathy; Phosphodiesterase 5 (PDE-5) Inhibitor; Pfizer; Sildenafil
History Sildenafil was first synthesized by pharmaceutical chemists working at Pfizer. It was initially studied for use in hypertension and angina. Phase I clinical trials suggested that the drug had little effect on angina but could induce penile erection. Sildenafil (Viagra®) was patented in 1996 and approved by the FDA for use in erectile dysfunction (ED) in March, 1998. Vardenafil (Levitra®) was approved by the FDA for treatment of erectile dysfunction in August, 2003 and tadalafil (Cialis®) in November, 2003. Avanafil (Stendra®) was approved in April, 2012. Udenafil (Zydena) is not FDA approved for sale in the United States, but is available in Korea, Russia and the Philippines.
Date 2015-02
Language eng
Format application/pdf
Type Text
Relation is Part of NANOS Annual Meeting Journal Club, 2015
Collection Neuro-Ophthalmology Virtual Education Library - Walsh Session Annual Meeting Archives https://novel.utah.edu/Walsh/index3.html
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-6232
Rights Management Copyright 2015. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6613wxq
Setname ehsl_novel_fbw
ID 179289
Reference URL https://collections.lib.utah.edu/ark:/87278/s6613wxq
Back to Search Results