Actinomyces Orbital Osteomyelitis in the Setting of Multiple Myeloma and Bisphosphonate-Related Osteonecrosis

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Title Actinomyces Orbital Osteomyelitis in the Setting of Multiple Myeloma and Bisphosphonate-Related Osteonecrosis
Creator Katherine S. Hu; Sangeeta Khanna
Affiliation Department of Ophthalmology, Saint Louis University School of Medicine, St. Louis, Missouri
Abstract Actinomyces is a genus of filamentous, branching gram-positive bacteria that are commensal organisms in the oral cavity, although they may become invasive in both immunocompetent and immunocompromised patients (1). Infection may extend from cervicofacial foci along tissue planes, through the foramina or directly through bone, yet Actinomyces is a rare cause of orbital infection (2-4). We describe a patient with orbital osteomyelitis and vision loss in the setting of bisphosphonate-related osteonecrosis of the jaw (BRONJ), a poorly understood disease process that has been linked to Actinomyces osteomyelitis.
Subject Actinomyces / isolation & purification; Actinomycosis / diagnosis; Actinomycosis / etiology; Actinomycosis / microbiology; Aged; Biopsy; Bisphosphonate-Associated Osteonecrosis of the Jaw / complications; Eye Infections, Bacterial / diagnosis; Eye Infections, Bacterial / etiology; Eye Infections, Bacterial / microbiology; Humans; Magnetic Resonance Imaging; Male; Multiple Myeloma / complications; Orbital Diseases / diagnosis; Orbital Diseases / etiology; Orbital Diseases / microbiology; Osteomyelitis / diagnosis; Osteomyelitis / etiology*; Osteomyelitis / microbiology
OCR Text Show
Date 2019-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, March 2019, Volume 39, Issue 1
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6x11xg2
Setname ehsl_novel_jno
ID 1595774
Reference URL https://collections.lib.utah.edu/ark:/87278/s6x11xg2
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